Search results for "CD 1"

The HDAC6 Inhibitor tubacin induces release of CD133+ extracellular vesicles from cancer cells

2017

Tumor-derived extracellular vesicles (EVs) are emerging as an important mode of intercellular communication, capable of transferring biologically active molecules that facilitate the malignant growth and metastatic process. CD133 (Prominin-1), a stem cell marker implicated in tumor initiation, differentiation and resistance to anti-cancer therapy, is reportedly associated with EVs in various types of cancer. However, little is known about the factors that regulate the release of these CD133+ EVs. Here, we report that the HDAC6 inhibitor tubacin promoted the extracellular release of CD133+ EVs from human FEMX-I metastatic melanoma and Caco-2 colorectal carcinoma cells, with a concomitant dow…

Presence of endothelial progenitor cells, distinct from mature endothelial cells, within human CD146+ blood cells.

2006

SummaryCD146 is an adhesion molecule present on endothelial cells throughout the vascular tree. CD146 is also expressed by circulating endothelial cells (CECs) widely considered to be mature endothelial cells detached from injured vessels. The discovery of circulating endothelial progenitor cells (EPCs) originating from bone marrow prompted us to investigate whether CD146 circulating cells could also contains EPCs. We tested this hypothesis using an approach combining elimination of CECs by an adhesion step, followed by immunomagnetic sorting of remaining CD146+ cells from the non adherent fraction of cord blood mononuclear cells. When cultured under endothelial-promoting conditions, these …

Younger is better? Isolation and phenotypical characterization of mesenchymal stem cells from the Wharton's jelly of pre-term human umbilical cords

2014

Pirmā tipa cukura diabēta pacientu fiziskās aktivitātes līmeņa ietekme uz depresijas simptomiem

2021

Maģistra darba mērķis - Noskaidrot CD 1 pacientu fiziskās aktivitātes līmeņa asociāciju ar depresijas simptomiem. Pētījuma hipotēze - Fiziski aktīviem CD1 pacientiem ir zemāks depresijas pazīmju līmenis. Uzdevumi: 1.Noskaidrot CD 1 pacientu fiziskās aktivitātes līmeni; 2.Noskaidrot vai fiziskā aktivitāte un tās intensitāte ir saistīta ar depresijas simptomiem pacientiem ar CD 1; 3.Noskaidrot kādi faktori ir asociēti ar CD 1 pacientu depresijas simptomu attīstību; 4.Noskaidrot kādi faktori ir asociēti ar CD 1 pacientu fizisko aktivitāti. Pētījumā dizains - šķērsgriezuma pētījums ar sekundāro datu apstrādi. Iegūtie dati tika analizēti – ar SPSS, Excel, Word process. Pētījumā piedalījās 346 pa…